Leucovorin is indicated to diminish the toxicity and counteract the effect of inadvertently administered overdosages of methotrexate.
Find out about Methotrexate.
Methotrexate use has rarely caused serious (sometimes fatal) side effects.such as lung problems.lung infections (Pneumocystis jiroveci pneumonia).skin reactions.diarrhea.and mouth sores (ulcerative stomatitis). (See also Side Effects section.)
Leucovorin is indicated to diminish the toxicity and counteract the effect of inadvertently administered overdosages of methotrexate. Leucovorin administration should begin as promptly as possible. As the time interval between methotrexate administration and leucovorin initiation increases.the effectiveness of leucovorin in counteracting toxicity buy methotrexate 2.5 mg 24. Monitoring of the serum methotrexate concentration is essential in determining the optimal dose and duration of treatment with leucovorin.
Methotrexate is bound in part to serum albumin after absorption.and toxicity may be increased because of displacement by certain drugs such as salicylates.sulfonamides.phenytoin.and some antibacterials such as tetracycline.chloramphenicol and para-aminobenzoic acid. These drugs.especially salicylates and sulfonamides.whether antibacterial.hypoglycaemic or diuretic.should not be given concurrently until the significance of these findings is established.
In rare instances.buy methotrexate 2.5 mg 24 drug may also cause liver problems when it is used for long periods of time. If you are using methotrexate long term.a liver biopsy is usually recommended.
This medicine may make you bleed.bruise.or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.
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